You may ask what the health of your mouth has to do with your overall health? But in a word, plenty! A look inside your mouth, or a swab of saliva can tell your doctor so much about what's going on inside the rest of your body, this often serves as a helpful vantage point for detecting the early signs and symptoms of systemic disease. Systemic conditions such as AIDS or diabetes, for example, often first become apparent as mouth lesions or other oral problems. In fact, according to the Academy of General Dentistry, more than 90 percent of all systemic diseases produce oral signs and symptoms.